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Trazodone is an atypical antidepressant that is commonly known for its role in treating insomnia. It is a useful medication for treating mental health issues and tends to offer relief from conditions such as depression and anxiety. While this substance helps provide therapeutic benefits, there is a risk of trazodone addiction and abuse by most people.

Like any other drug, taking such a drug to deal with depression issues can see people becoming addicted to it. For this reason, it is essential to understand the duration of the Trazodone effect and its effect on individuals facing such challenges; by knowing this, individuals, caregivers, and healthcare professionals can be equipped with essential insights on how to navigate the complexities that these drugs bring.

In this guide, we explore the importance of taking only the required dose of Trazodone and how to tackle Trazodone abuse. It also highlights why it is essential to seek robust support systems to help mitigate the potential risks of abusing this potent drug – let’s get started!

How Long Does Trazodone Stay In Your System?

Tradozone is heavily metabolized and activated in the liver by the CYP3A4 enzyme. This enzyme plays a crucial role in metabolizing many medications in the body. Trazodone becomes Trazodoneetabolites when metabolized, including the active metabolite m-chlorophenyl piperazine (mCPP). This metabolite contributes to some of the therapeutic effects of Trazodone. Some other metabolites identified include the dihydrodiol metabolite and carboxylic acid. 

The rate at which Trazodone is metabolized in the liver varies from person to person. Some factors that determine how the metabolism will take place include a person’s age, genetics, and the presence of other medications.

Trazodone Elimination

After metabolism, Trazodone is usually eliminated, mainly urine and feces from the body. Only less than 1% of an oral dose is excreted unchanged in the urine elimination half-life- the time it takes for half of the drug takes about 5 to 9 hours to reach the body.

Approximately 60 to 70% of radiolabeled is excreted as urine within 48 hours. Additionally, 9 to 29% can be excreted as feces within 60 to 100 hours. 

The kidneys take up most of the elimination process, about 70 to 75% of Trazodone excretion. This is according to an FDA medical review. Also, it has been reported that about 21% of Trazodone has been excreted as fecal matter, and 0.13% of the parent drug is eliminated in the urine as an unchanged drug. 

Some factors that can impact the elimination of Trazodone from the body include an individual’s liver, kidney, and overall function. People with impaired liver or kidney function are likely to experience slower elimination of the drug so that it might stay a little longer in the body.

Some medications may affect the elimination of Trazodone from the body. For instance, CYP3A4, the enzyme responsible for metabolizing Trazodone, can slow down its elimination and increase its concentration in the body. On the other hand, inducers of CYP3A4 can accelerate the metabolism and elimination of Trazodone, therefore reducing its effectiveness/

To ensure safe and effective medication use, it is essential to understand the metabolism and elimination of Trazodone.

Trazodone Abuse: Half-Life and Effects of Detection

The half-life of Trazodone is approximately 9 to 10 hours. This means that the amount of drugs in the system will drop by half every 9 to 10 hours. However, it is essential to note that half of life can change from person to person. Usually, it can take about five half-lives for most drugs to be eliminated in the body. Therefore, for Trazodone to be eliminated from the body, it can take 25 to 45 hours. Specific factors affecting the half-life of Trazodone include age, metabolism, liver function, and other medications.

  • Age – Older people take longer to remove trade zone from the body, which may be due to the metabolism and overall health of a person
  • Liver and Kidney Function – The liver and kidney are essential when it comes to the detoxification and filtering process. Trazodone will likely move out of your body faster when your liver and kidney are healthy.
  • Weight – The weight of your body will determine how long Trazodone stays in your system before it is eliminated. Heavier people need more of the drug to reach the same blood concentrations.

Trazodone Detection 

Trazodone can stay detected in the system for up to 90 days. It is rarely screened in the drug toxicology screens, but it’s still traceable in the body after a while. 

Trazodone Detection in Urine

One of the most commonly used drug screening methods is a urine test. Tradozone usually breaks down in the body quickly. However, the metabolites produced linger in the body for longer. In the ruine, the Trazodone metabolites can be detected for up to 26 days.

Trazodone Detection in the Blood

Blood tests are less commonly used to detect drugs in the system. This is because substances are metabolized in drugs faster than with other tests. Usually, blood tests can detect Trazodone for up to 3 days after the last use.

Detection in Saliva

Saliva can pick up drugs faster than other drug tests. Most of the time, it has been able to detect substances in four hours since the last use. Trazodone stays in the saliva longer than in blood and can be detected for up to 4 days after use.

Detection in Hair

Hair follicles are fast-growing cells. They can pick up metabolites from drugs and store them for a longer time than in other drug tests. Trazodone can be detected in the hair follicles up to 90 days after use. Even though hair tests can find Trazodone within 90 days or longer, it can take more than two weeks or more for these substances to appear on the test.

Factors Affecting Trazodone Detection Time

Some of the factors that can determine the detection rate of Trazodone include:

  • Amount of Trazodone an individual has taken
  • How long a person has taken Trazodone
  • The strength of the dose of Trazodone used
  • Gender
  • Age
  • Other substances, such as alcohol, are taken with Trazodone
  • Body mass index
  • Pre-existing medical conditions

While Trazodone has a short window period, its presence in drug tests can raise concerns, especially when it comes to substance abuse. People can attempt to misuse it or combine it with other substances to enhance its effects. This might lead to dependence on the drug and addiction.

It is also worth noting that relying solely on drug tests to monitor Trazodone use may not capture the full picture of substance abuse. Some people tend to manipulate their medication intake to avoid it from being detected in the body.

Side Effects of Trazodone Addiction and Abuse

When overused or misused, Trazodone will likely cause many effects on an individual’s body. In most cases, these effects do not last long or are life-threatening. However, in some cases, the medications may cause serious side effects which require medical attention. Some of the common side effects associated with Tradozone abuse include:

  • Blurred vision
  • Sweating
  • Weight loss
  • Drowsiness
  • Swelling
  • Stuffy nose
  • Diarrhea and constipation
  • Dry mouth
  • Sexual dysfunction
  • Skin rashes
  • Slow heartbeats
  • Easy bruising
  • Cardiac arrhythmia
  • Low sodium levels

Some individuals may experience an overdose when using Trazodone. Some of the symptoms of the overdose include

  • Confusion
  • Agitation
  • Shivering
  • Twitching muscles
  • Rapid heart rate.

Seeking Help for Trazodone Addiction and Abuse

As said earlier, Trazodone is an effective drug that acts as an antidepressant. However, people can develop a dependence on it when they overuse it, leading to addiction. In some cases, Trazodone overdose can be fatal. For this reason, it is essential to seek treatment if needed. 

Seeking help from a reputable treatment center can help prevent complications in the future. A treatment center offers a safe and supportive environment for individuals to address their substance use disorders. In these centers, there are doctors, therapists, and counselors who work together to treat addiction. They can assess an individual’s unique needs and deduce personalized treatment plans that suit their circumstances.

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Some services individuals will get at a treatment center to help individuals overcome Trazodone abuse include detoxification programs, which allow them to manage withdrawal symptoms safely, and individual and group therapy sessions to help address underlying issues that are leading to the addiction. Also, individuals are put through educational programs to promote long-term recovery and relapse prevention strategies.

Also, treatment centers often use holistic healing and cognitive behavioral therapy ( CBT) to address and help individuals with Trazodone abuse. These approaches help individuals develop coping skills and make them more self-aware, leading to better recovery.

So, if you or your loved one are facing Trazodone abuse and want help, then seek it from a reputable healing center.

Trazodone Common Myths and Misconceptions

Some of the common myths and misconceptions about Trazodone include the following:

  • Trazodone is Not Addictive – Well, while some people believe that Trazodone is not addictive, the reality is that it is indeed addictive, especially because it causes dependence and misuse.
  • Trazodone Cures Substance Abuse – Contrary to the belief that Trazodone helps cure substance abuse, the truth is that it does not. This drug is mainly used to treat mental health conditions such as depression and anxiety.
  • Trazodone is Prescribed to Help You Sleep – The truth is that no doctor will prescribe Trazodone to help you sleep. However, this drug may make you sleepy.

Understanding the complexities of Trazodone use, including its metabolism, elimination, and effects on detection, is crucial for safe and effective treatment and addiction recovery. Seeking support from reputable rehab centers like Still Waters Wellness Group can greatly help individuals struggling with Trazodone addiction. To get more information about Trazodone abuse treatment and admission, contact us today. (800) 563-8983